Choosing a subset of flops to represent the whole game​

There are 22100 possible flops in Holdem out of which 1755 are strategically different. This is quite a big number which makes attempts to approximate preflop EV for chosen spots as well as upcoming preflop solving quite a difficult task. One needs a few terabytes of RAM to fit even very simple games (assuming full postflop play) and using a disc storage slows things down very significantly.